Is it cost effective to screen women for syphilis twice during pregnancy?

The UK National Screening Committee (UK NSC) asked Aquarius to assess the costs and benefits of two different approaches to antenatal screening for syphilis.

We compared the current strategy – screening in the first trimester only – with an alternative strategy – screening in the first trimester and a repeat screen later in pregnancy.  The results of our cost-effectiveness analysis were recently published in BMJ Open and are now available online.

Continue reading

Could we optimise testing for gonorrhoea to avoid the use of last-line antibiotics?

Ceftriaxone is the first-line treatment for gonorrhoea but there are few alternative treatments available should ceftriaxone resistance become widespread. Aquarius created a model to explore how point-of-care testing could be used to diagnose gonorrhoea and at the same time test for antibiotic susceptibility, which could allow the use of previously abandoned antibiotics for many patients, thereby sparing ceftriaxone use.

Continue reading

How can economic models inform decision-making about screening programmes?

Dr Elisabeth Adams, Managing Director and Founder of Aquarius Population Health, spoke at a continuing medical education webinar for health professionals hosted on September 23,2020 by the Consortium for Infectious Disease Control (CIDC).  

With increasing demands on time and resources, decision-makers in healthcare need information about how to create a safe, effective and cost-effective screening programme. Elisabeth discussed how theoretical quantitative evidence from health economic evaluations and models can inform decision-making, and guide policy decisions at local, regional, national and international levels in the absence of empirical data.

Continue reading

Aquarius part of collaborative NIHR grant to evaluate Odin Vision’s artificial intelligence technology to fight bowel cancer

In the UK, 42,000 new diagnoses and 16,000 deaths occur from bowel cancer each year. Bowel cancer is the second most common cause of cancer death in the UK, comprising over 10% of all deaths due to cancer. (1)

A recent study found that almost one third of bowel cancer patients experience an avoidable delay in their diagnosis. (2) Earlier detection of bowel cancer can result in better patient outcomes.  With the goal of achieving earlier diagnosis of cancer and saving more lives, the NIHR AI in Health and Care Award was announced by the Health Secretary, the Rt Hon Matt Hancock MP, at London Tech Week. The National Institue for Health research (NIHR) has awarded £140M in funding to back development of the most promising technologies in artificial intelligence (AI).  Odin Vision Ltd was awarded a grant to support the development of their new AI technology, the CADDIE system, which uses machine learning to assist doctors in identifying and removing abnormalities during a colonoscopy. (3)

Continue reading

Sexual Health

Improving clinical decision making and patient management

The Aquarius team has a breadth of experience in sexual health research and our work in this area has informed international policy and patient care. 

Projects within this field include health economic evaluations, assessing the impact of new innovations such as rapid diagnostics, measuring the burden of disease, evaluating alternative screening strategies and creating interactive tools to inform decisions making around adoption of new technologies.

Read more

How much would community-based screening for chlamydia and gonorrhoea cost?

We collaborated with St George’s, University of London, on a NIHR-funded ‘Test n Treat’ (TnT) study. This study assessed the cost of providing same-day chlamydia and gonorrhoea testing and treatment service at higher education colleges. The paper presenting this work was published in BMC Health Services Research and is now available online.

Continue reading

Using an mRNA versus DNA test in the English cervical screening programme can save £15m annually and reduce unnecessary testing

The results of our economic evaluation comparing the use of mRNA and DNA assays in screening for cervical cancer in England were published in BMJ Open and are now available online. Results show large cost savings from avoiding unnecessary testing and follow-up, which can benefit women and healthcare services.

Continue reading

Aquarius supports education charity Homework Hotline as they evaluate their tutoring services

At Aquarius we understand the importance of developing a love of learning from an early age. The education we receive at school creates the foundation for later studies and professional development. That’s why we decided to work pro bono with Homework Hotline, an educational charity that provides free after school tutoring to any school aged child in the state of Tennessee, USA.

Continue reading

Aquarius welcomes new team members

We’re pleased to have welcomed two new members of the Aquarius team since moving to our new office in Tileyard in 2018.

Georgie Weston joined the team in October as an Associate, having recently completed her Master of Public Health at the London School of Hygiene and Tropical Medicine, awarded with Distinction. Georgie has experience working with a range of organisations, including the WHO, health charities, and large pharmaceutical companies where she worked within communications and marketing strategy.

Continue reading