Exploring an alternative way to triage samples within cervical cancer screening
Our analysis comparing the costs of using DNA methylation testing for triage instead of liquid-based cytology (LBC) within the Netherlands cervical screening programme has now been published as an open access peer reviewed publication in the journal Diagnostics. Self-sample collection for human papillomavirus (HPV)-primary cervical screening has been adopted in some settings to complement traditional Read More >
Looking at the cost implications of using PCR-based respiratory panel assays for patients admitted to hospital with pneumonia in the UK, France and Spain
Our paper on the cost of using PCR-based respiratory panel assays for patients with pneumonia was published this week in BMC Pulmonary Medicine. This work, funded by the Innovative Health Initiative (IHI), compared the cost of using standard diagnostic tests with the cost of using either an upper respiratory pathogen PCR-based panel test, a lower Read More >
Economic evaluation of different sampling strategies for cervical cancer screening
Our recently published paper comparing different cervical screening options in England provides early economic evidence that sample self-collection may be a cost-effective option for cervical cancer screening programmes. This work supports decision-making for cervical screening programmes. Cervical cancer is the fourth most common cancer among women worldwide, yet most cases are preventable through early detection Read More >
Exploring the cost-effectiveness of focused ultrasound in treating Essential Tremor in England
Medically refractory Essential Tremor (mrET) is the most common movement disorder affecting approximately 1 million in the United Kingdom and can be disabling. Medical treatment is not always successful at controlling tremors. Deep Brain Stimulation (DBS) is a proven neurosurgical treatment; however, the risks of surgery and anaesthesia mean some patients are ineligible for DBS. Read More >
Novel diagnostics may be a cost-effective intervention for sepsis management to reduce bed days and reduce inappropriate prescribing of antibiotics.
Sepsis is a life-threatening condition in response to infection. Without rapid treatment, sepsis can result in tissue damage, organ failure or death. Speed is of the essence for sepsis management and faster diagnosis of specific pathogens may help ensure patients receive the most appropriate treatments as soon as possible. Reducing the use of broad-spectrum antibiotics Read More >
Comparing the costs and benefits of the use of an mRNA HR-HPR assay to a DNA HR-HPV assay in the proposed cervical screening programme in France
Cervical cancer is the fourth most common cancer in women aged 15 to 44 years in France. With the implementation of cytology-based cervical screening, cervical cancer incidence and mortality have decreased over time, however, cervical cancer remains a concern. As cervical cancer is primarily caused by persistent infection with high-risk human papillomaviruses (HR-HPV), guidelines for Read More >
What are the common barriers to optimal COPD care?
Chronic obstructive pulmonary disease (COPD) is a preventable, progressive respiratory disease, characterized by irreversible airflow limitation and symptoms such as dyspnoea, persistent cough, and sputum production. COPD was the third leading cause of mortality worldwide in 2019 (1), responsible for 3.23 million deaths (2). Despite the availability of the Global Initiative for Chronic Obstructive Lung Read More >
User experience and workflow performance: a pilot evaluation of the Genius Digital Diagnostics System for screening cervical cytology samples
It is generally understood that the cytology work process can be stressful and fatiguing affecting technicians’ performance and job satisfaction on a day-to-day basis and in the longer term. This study assessed the performance and user experience of cytotechnologists (CTs) reviewing liquid-based cytology samples using a new digital cytology platform Genius Digital Diagnostics System (Genius Read More >
Analysing the COPD care pathway in Japan, Canada, England and Germany: a global view
Aquarius Population Health are delighted to be collaborating with AstraZeneca on a poster session at this year’s European Respiratory Society International Congress. Our research, based on clinician interviews and local data reviews, advances our understanding of COPD care pathways in Japan, Canada, England and Germany, and identifies cross cutting barriers to optimal COPD care, which Read More >
Modelling the costs and benefits of an mRNA compared to a DNA high-risk HPV assay in a hypothetical HPV primary screening algorithm in Ontario, Canada
Cases of cervical cancer in Canada have decreased recently as a result of cytology-based screening programs. However, cervical cancer remains a relatively common and preventable cause of cancer in women. As cervical cancer is primarily caused by persistent genital infection with high-risk (HR) human papillomaviruses, Ontario Health has been evaluating implementing HPV-based testing in cervical Read More >