Aquarius Population Health

Self-sampling for cervical cancer screening – what is it and what does evidence from Europe tell us about whether it provides any benefits compared to traditional ways of screening?

Regular screening is crucial for preventing cervical cancer or identifying cancer at an early stage, when treatment is most likely to be successful. Screening is particularly important for women who did not receive the HPV vaccine; in the UK, that means most women over the age of 30. Many European countries, including the UK, have Read More >

Exploring an alternative way to triage samples within cervical cancer screening

Our analysis comparing the costs of using DNA methylation testing for triage instead of liquid-based cytology (LBC) within the Netherlands cervical screening programme has now been published as an open access peer reviewed publication in the journal Diagnostics. Self-sample collection for human papillomavirus (HPV)-primary cervical screening has been adopted in some settings to complement traditional Read More >

Comparing the costs and benefits of the use of an mRNA HR-HPR assay to a DNA HR-HPV assay in the proposed cervical screening programme in France

Cervical cancer is the fourth most common cancer in women aged 15 to 44 years in France. With the implementation of cytology-based cervical screening, cervical cancer incidence and mortality have decreased over time, however, cervical cancer remains a concern. As cervical cancer is primarily caused by persistent infection with high-risk human papillomaviruses (HR-HPV), guidelines for Read More >

User experience and workflow performance: a pilot evaluation of the Genius Digital Diagnostics System for screening cervical cytology samples

It is generally understood that the cytology work process can be stressful and fatiguing affecting technicians’ performance and job satisfaction on a day-to-day basis and in the longer term. This study assessed the performance and user experience of cytotechnologists (CTs) reviewing liquid-based cytology samples using a new digital cytology platform Genius Digital Diagnostics System (Genius Read More >

Modelling the costs and benefits of an mRNA compared to a DNA high-risk HPV assay in a hypothetical HPV primary screening algorithm in Ontario, Canada

Cases of cervical cancer in Canada have decreased recently as a result of cytology-based screening programs. However, cervical cancer remains a relatively common and preventable cause of cancer in women. As cervical cancer is primarily caused by persistent genital infection with high-risk (HR) human papillomaviruses, Ontario Health has been evaluating implementing HPV-based testing in cervical Read More >

Improving patient care with rapid point of care tests

Dr Elisabeth Adams, Managing Director of Aquarius Population Health, presented on opportunities for rapid tests in influenza and HPV at international conferences in June. This has been a busy week for the Aquarius Population Health team. We had two posters at the Society for Medical Decision Making in London (12-15th June), which Elisabeth presented. The Read More >