Transforming clinical decisions

We help you visualise current patient care pathways and benchmark them against guidelines. Working together we can understand how current practice might be optimised to yield better outcomes for patients and more efficient services.

Case Studies

Cervical screening and HPV testing: Opportunities for rapid tests

We explored the use of a rapid, on-demand human papillomavirus (HPV) test. Interviews with UK experts revealed that a co-located, on-demand HPV test following cytology could reduce the time to cervical screening results by up to a week, with a near-patient primary HPV test followed by cytology triage could radically change the testing paradigm. A follow-up tool we built in Excel was used to understand cervical screening burden and HPV testing across Europe.

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The cost of pelvic inflammatory disease and potential cost-savings of chlamydia screening

We worked with clinicians from St Georges University who had published a trial estimating the incidence of pelvic inflammatory disease (PID) among women screened and unscreened for chlamydia. Patient data was analysed, and the average cost of managing PID was estimated to be £163 in community and hospital settings, and that over £60,000 could be saved in London alone from screening for chlamydia. This paper has been cited widely and results have informed policy and further modelling studies.

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Estimating the true costs of splitting HIV antiretroviral drugs

There is a temptation to switch to cheaper generic antiretroviral drugs compared to fixed-dose combination therapy for HIV patients in the interests of cost savings. However, in our analysis we found that there were no costs saved when including all patient care including drugs, additional clinic visits and monitoring. We also found that switching may cause confusion for some patients, risking loss of adherence. This evidence can help commissioners make better policy decisions about drug provision.

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Understanding Idiopathic Pulmonary Fibrosis patient care delivery and costs

We explored patient pathways for the diagnosis, management and monitoring of idiopathic pulmonary fibrosis (IPF) across England, based on NICE pathways, and interviews with healthcare staff from 14 hospital trusts. Data were used in our in-house tool to estimate the cost of pathways, compared to tariff reimbursement. We found large variation across England in how services for IPF patients are delivered, variation compared to the NICE pathway, and costs >40% more than what is currently reimbursed.

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Increased efficiency and improved treatment for stable HIV patients in England

Collaborators at St Georges Hospital wanted to understand the impact of changing service provision for stable HIV patients, as no evidence existed on what was best for clinics. We built a tool in Excel, and results indicated that 6-monthly appointments and 3-monthly home delivery of drugs is the cheapest option and could yield £2000 savings per patient, translating to an annual cost reduction of ~£8 million for the estimated 4000 eligible patients not currently on home delivery in England in 2012.

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The benefits and cost-savings of a new point-of-care test for chlamydia and gonorrhoea

We developed an understanding of how sexual health clinics in England could use a rapid point of care test for two common sexually transmitted infections. We defined the current patient care pathways and found that the pathways could be streamlined and costs of care reduced by using point-of-care tests. The economic model developed by Aquarius Population Health showed that the test could deliver £10 million in cost savings, and give far more effective management of chlamydia and gonorrhoea at a population level.

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Publications

Rapid testing and treatment for sexually transmitted infections improve patient care and yield public health benefits

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Point-of-care tests for infectious diseases: Barriers to implementation across three London teaching hospitals

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Modelling the burden of non-muscle-invasive bladder cancer in Europe

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Mapping the diagnostic pathway for breast cancer in England and comparison to Europe

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Providing integrated HIV treatment and care for stable patients in general practice

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How can European countries improve cervical cancer prevention for women?

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Exploring the value of a rapid, on-demand test for the detection of human papillomavirus

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The financial and service implications of splitting fixed-dose antiretroviral drugs – a case study

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The cost and tariff reimbursement of idiopathic pulmonary fibrosis in England

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Treatment for stable HIV patients in England: can we save costs and improve patient care?

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The cost-effectiveness of point of care tests for chlamydia and gonorrhoeae in sexual health clinics

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Cost effectiveness of screening for Chlamydia trachomatis in Ireland

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What is the cost of pelvic inflammatory disease and how much could be prevented by screening for chlamydia?

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News

SBRI2 Grant Press Release PRESS RELEASE: Aquarius Population Health wins a prestigious SBRI grant from Innovate UK - Work has begun to develop a digital value proposition tool for a novel rapid sexually transmitted infection (STI) test London, UK, 14 August 2017 Aquarius Population Health, a leading independent health economics consultancy, has recently been awarded an 18-month Innovate UK grant in collaboration with Atlas Genetics Ltd and the Applied Diagnostic Research and Evaluation… Read More
Point-of-care tests for STI Evaluating the use AMR POCT in treatment of gonorrhoea - Aquarius Population Health recently worked with the Applied Diagnostic Research & Evaluation Unit (ADREU) at St. Georges, University of London, to assess the cost-effectiveness of six hypothetical strategies for using antimicrobial resistance point-of-care testing to guide the treatment of gonorrhoea.  Our findings were presented at the STI & HIV World Congress in Rio de Janeiro,… Read More
Point of Care Testing Point of care testing: Disruptive innovation – is the NHS ready for it yet? - Our Managing Director, Elisabeth Adams, spoke in November about the importance of exploring the health economics of point of care testing (POCT) at the Royal Society of Medicine Telemedicine and eHealth event in London. The video of her presentation is now online – view the full talk here. Why is it important to explore the… Read More