Is it cost effective to screen women for syphilis twice during pregnancy?

The UK National Screening Committee (UK NSC) asked Aquarius to assess the costs and benefits of two different approaches to antenatal screening for syphilis.

We compared the current strategy – screening in the first trimester only – with an alternative strategy – screening in the first trimester and a repeat screen later in pregnancy.  The results of our cost-effectiveness analysis were recently published in BMJ Open and are now available online.

Continue reading

Could we optimise testing for gonorrhoea to avoid the use of last-line antibiotics?

Ceftriaxone is the first-line treatment for gonorrhoea but there are few alternative treatments available should ceftriaxone resistance become widespread. Aquarius created a model to explore how point-of-care testing could be used to diagnose gonorrhoea and at the same time test for antibiotic susceptibility, which could allow the use of previously abandoned antibiotics for many patients, thereby sparing ceftriaxone use.

Continue reading

How can economic models inform decision-making about screening programmes?

Dr Elisabeth Adams, Managing Director and Founder of Aquarius Population Health, spoke at a continuing medical education webinar for health professionals hosted on September 23,2020 by the Consortium for Infectious Disease Control (CIDC).  

With increasing demands on time and resources, decision-makers in healthcare need information about how to create a safe, effective and cost-effective screening programme. Elisabeth discussed how theoretical quantitative evidence from health economic evaluations and models can inform decision-making, and guide policy decisions at local, regional, national and international levels in the absence of empirical data.

Continue reading