Ceftriaxone is the first-line treatment for gonorrhoea but there are few alternative treatments available should ceftriaxone resistance become widespread. Aquarius created a model to explore how point-of-care testing could be used to diagnose gonorrhoea and at the same time test for antibiotic susceptibility, which could allow the use of previously abandoned antibiotics for many patients, thereby sparing ceftriaxone use.Continue reading
Aquarius Population Health recently worked with the Applied Diagnostic Research & Evaluation Unit (ADREU) at St. Georges, University of London, to assess the cost-effectiveness of six hypothetical strategies for using antimicrobial resistance point-of-care testing to guide the treatment of gonorrhoea. Our findings were presented at the STI & HIV World Congress in Rio de Janeiro, Brazil. [Wednesday 12th July, Session 15: STI/HIV testing and management].
In a study commissioned by the Review on Antimicrobial Resistance, Aquarius Population Health worked with modellers at the University of Bristol to create a mathematical model. The model was used to assess the economic implications and treatment impact of introducing a hypothetical antimicrobial resistance (AMR) point-of-care test (POCT) for gonorrhoea. Results of the study were published this week in BMJ Open.
Antimicrobial resistance (AMR) has been described as one of the world’s greatest threats to human and animal health. Some reports suggest that by 2050, AMR could kill around 10 million people each year worldwide. Public health leaders warn we could enter a ‘post-antibiotic’ era where easily treatable common infections become untreatable.
Part 2: What, if anything, can we do as individuals to help combat AMR?
In the second part of this article, we explore what we can do to combat AMR.
Don’t get ill.
That might sound ridiculous, since no one wants to get ill. However as individuals, we can reduce our risk of picking up an infection and reduce our need for antimicrobials. One of the simplest, but probably the most difficult, is to eat a healthy diet and stay physically active. At the Aquarius office, we have a communal fruit bowl to encourage us to eat healthier snacks. We compete in a weekly fitness challenge to see who walks the most steps, encouraging us all to be more active.
Part 3: What role does innovation such as rapid diagnostics have in preventing AMR?
Just as new technology has helped us in the fight against global warming (fuel efficiency, clean energy etc.), technology can also help us in the fight against antimicrobial resistance (AMR). One such area is rapid diagnostics – identified as a key intervention for reducing AMR in the government’s 2016 Review of Antimicrobial Resistance.